Hepatitis B Replication Part 1 of 3 #usmle

There is a receptor for the hepatitis B virus on the cell. Once attached the nucleocapsid goes into the cells and uncoats. The partially dsDNA hepatitis B virus goes into the nucleus where the remainder of the DNA is completed where it is covalently completed circular DNA cccDNA. Now it is a double stranded DNA. The cccDNA is used by the hepatitis B virus for transcription of the nucleocapsid. The hepatitis B Virus can then go back into the nucleus or go into the Golgi apparatus to get a new envelope. The virus than exits the cell using exocytosis.